Browsing UW Milwaukee Electronic Theses and Dissertations by Author "A. Andy Pacheco"

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Mechanism of the Hydroxylation Reactions Catalyzed By 4-Hydroxyphenylpyruvate Dioxygenase and Hydroxymandelate Synthase

Shah, Dhara D. (2014-08-01)

4-Hydroxyphenylpyruvate dioxygenase (HPPD) and Hydroxymandelate synthase (HMS) carry out highly similar complex dioxygenation reactions using the substrates, 4-hydroxyphenylpyruvate (HPP) and dioxygen. HPPD catalyzes ...
Modification of Pyrimidine and Purine Nucleotides By "Click" Chemistry: Design, Synthesis and Properties Study

Haque, Mohammad Mojibul (2014-12-01)

This dissertation consists of three main parts, totaling five chapters, and focuses on developing novel nucleosides via "click" chemistry and studying their potential biological properties. Chapter three describes the ...