UW Milwaukee Electronic Theses and Dissertations
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TARGETING CDKN1A WITH UC2288 TO ENHANCE OSTEOGENESIS: MECHANISTIC INSIGHTS, DIFFERENTIATION PATHWAYS, AND BIOMATERIAL-BASED DELIVERY STRATEGIES
(2026-05)p21 (CDKN1A) is a regulator of the cell cycle, involved in halting cell division, coordinating DNA repair, and contributing to both senescence and apoptosis. In addition to these functions, recent evidence indicates another ... -
DEVELOPING A NOVEL ROBOT-AIDED TELEREHABILITATION SYSTEM FOCUSING ON HUMAN UPPER LIMB
(2026-05)Stroke remains a leading cause of long-term disability worldwide, placing an unsustainable burden on healthcare systems due to the requirement for high-intensity, one-on-one manual therapy. While robot-assisted rehabilitation ... -
COMPARISON OF TRADITIONAL ANTENATAL CARE AND CENTERINGPREGNANCY®: MATERNAL AND INFANTS OUTCOMES
(2025-12)Background: Despite progress in antenatal care (ANC), maternal and infant health disparitiespersist, especially among socioeconomically marginalized populations. Traditional Antenatal Care (TAC), though effective for ... -
COMMUNICATIVE DIFFERENCES BETWEEN BLACK STUDENTS AT AN HBCU AND BLACK STUDENTS AT A PWI: A CO-CULTURAL PERSPECTIVE.
(2025-12)Black students’ experiences in higher education can vary significantly between predominantly White institutions (PWIs) and historically Black colleges and universities (HBCUs). The dissertation examines how these differing ... -
POLICING THE UNIVERSITY: A CRITICAL HISTORY OF CAMPUS LAW ENFORCEMENT
(2025-12)This thesis treats campus policing as a central mechanism of governance within contemporary public universities. Rather than a peripheral safety service, campus police operate as a system through which universities manage ... -
SYNTHESIS AND CHARACTERIZATION OF AL-CE METAL MATRIX COMPOSITES FOR HIGH TEMPERATURE APPLICATIONS
(2025-12)A primary advantage of Aluminum-Cerium alloys is their ability to retain their mechanical properties at elevated temperatures, i.e., in the range of 250 – 300 °C, compared to other aluminum alloys. This study focuses on ... -
DEVELOPMENT AND CONTROL OF A WHEELCHAIR-MOUNTED ASSISTIVE ROBOT WITH ADAPTIVE END-EFFECTORS FOR ACTIVITIES OF DAILY LIVING
(2025-12)In the United States, approximately 6 million adults use a wheelchair for mobility, and a substantial proportion experience reduced upper-limb function that limits their independence. More than three-fifths of these ... -
Effectiveness and Outcomes of Dialectical Behavior Therapy and Prolonged Exposure (DBT PE) among A Naturalistic Sample of Patients Receiving Comprehensive DBT
(2025-12)Dialectical Behavior Therapy (DBT; Linehan, 1993) and Prolonged Exposure (PE; Foa et al., 2019), and the relatively new, integrated treatment, Dialectical Behavior Therapy Prolonged Exposure (DBT PE; Harned, 2022) have all ... -
STRUCTURAL DESIGN OF HYBRID COMPOSITE SANDWICH SYSTEMS: A DESIGN METHODOLOGY FOR LAYUP OPTIMIZATION, LOAD TRANSFER ENHANCEMENT, AND INTEGRATION OF ADDITIVELY MANUFACTURED INSERTS IN MECHANICAL JOINTS
(2025-12)To expand into non-traditional industries, sandwich composites must be competitive with metals in terms of material, production, operating, and ecological costs. This requires continued cohesive advancements in raw materials, ... -
IDENTIFICATION AND QUANTIATION OF CERAMIDES AND THE EFFECT OF ANTI-CANCER DRUGS ON THEIR LEVELS IN GLIOBLASTOMA USING MASS SPECTROMETERY
(2025-12)Glioblastoma (GBM) is one of the most common and aggressive forms of brain tumor. Prior studies from our lab found that carmofur is a promising candidate for suppressing GBM proliferation and inducing tumor cell death. ... -
A Description of Midwestern United States Nurse Educators' Perceptions of Cultural Safety
(2025-12)ABSTRACT A DESCRIPTION OF MIDWESTERN UNITED STATES NURSE EDUCATORS’ PERCEPTIONS OF CULTURAL SAFETY by Kathleen K. DeMuth The University of Wisconsin-Milwaukee, 2025Under the Supervision of Professor Jeana M. Holt Background: ... -
Rebellious Stripes: The American Flag in Activist Art, 1960-2025
(2025-12)In the 1760s, as desire for independence fomented, revolutionary groups adopted a proto-flag dubbed the Rebellious Stripes, with vertical white and red stripes symbolizing a desire for freedom. Once the United States flag ... -
INVERSE PROBLEMS IN ELECTROMAGNETICS: CASE STUDIES OF DEEP LEARNING-BASED SOURCE RECONSTRUCTION AND OBJECT COUNTING
(2025-12)In this thesis, two case-specific Electromagnetic (EM) inverse problems are investigated. The first inverse problem is the prediction of the number of wires randomly distributed within a square-shaped region of interest ... -
PART I: A CONCISE TOTAL SYNTHESIS OF MICROTUBULE INHIBITORS TRYPROSTATIN A, B AND THEIR ANALOGS PART II: EVALUATION OF AN APPROACH FOR THE C2 ALKYLATION OF GRAMINE
(2025-12)PART I: A CONCISE TOTAL SYNTHESIS OF MICROTUBULE INHIBITOR TRYPROSTATIN A AND B AND THEIR ANALOGSTryprostatins A and B are natural products that exhibit anticancer properties. They were originally isolated from Aspergillus ... -
Baby Julia Sets in Dynamical and Parameter Space for a Rational Family of Maps When Both Critical Orbits are Bounded
(2025-12)We study the family of complex rational functions known as Generalized McMullen maps, F_{n,a,b}(z) = z^n + a/z^n + b, for a ≠ 0 and n ≥ 3 fixed. First, we reveal and provide a combinatorial model for some new dynamical ... -
Preclinical Characterization of Therapeutic Candidates for Inflammatory Disease and Chemical Injury
(2025-12)Herein, I report the use of a cytotoxicity assay to rapidly evaluate the safety and biological activity of newly synthesized small molecules. Using cultured mammalian cells, overt toxicity was measured by quantification ... -
CLINICAL COMPETENCE AND CLINICAL ENVIRONMENT: A COMPARATIVE STUDY OF NURSE EXTERNS AND NON-EXTERNS
(2025-12)ABSTRACT CLINICAL COMPETENCE AND CLINICAL ENVIRONMENT: A COMPARATIVE STUDY OF NURSE EXTERNS AND NON-EXTERNS by Sherri Ann Hanrahan The University of Wisconsin-Milwaukee, 2025Under the Supervision of Professor Julia Snethen ... -
MACHINE LEARNING FOR RESOURCE ALLOCATION IN EMERGENCY DEPARTMENT
(2025-12)Emergency Departments (EDs) face constant pressure from unpredictable patient arrivals, limited beds, and staffing challenges. These issues often lead to longer ED stays, higher costs, and clinician burnout. While machine ... -
HYBRID JIT–CUDA GRAPH OPTIMIZATION FOR LOW-LATENCY LARGE LANGUAGE MODEL INFERENCE
(2025-12)Large Language Models (LLMs) deliver strong performance but suffer from high inference latency and unstable kernel-launch overhead. This the- sis introduces a Hybrid JIT–CUDA Graph Runtime that combines static CUDA Graph ... -
Synthesis and Characterization of Li3YCl6, Li3LaCl6, and Li3InCl6 Halide Electrolytes For All-Solid-State Lithium-Ion Batteries (ASSLIBs)
(2025-12)All-solid-state lithium-ion batteries (ASSLIBs) are considered a promising next-generation energy storage technology due to their improved safety, high energy density, and wider electrochemical stability compared to ...
