Browsing Student Research Day by Author "Laatsch, Bethany"
Now showing items 1-4 of 4
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Exploring the Effects of Monomer and Polymer Cosolutes on the Conformation of Escherichia coli Prolyl-tRNA Synthetase Using Intrinsic Tryptophan Fluorescence Spectroscopy
Johnson, Benjamin; Fossum, Carl; Liebau, Jessica; Liew, Aubrey; Laatsch, Bethany; Hati, Sanchita (2021-04) -
How Does Varying Sizes and Concentrations of Poly(Ethylene Glycol) Affect the Conformation and Function of the Enzyme Escherichia Coli Prolyl-Trna Synthetase?
Liebau, Jessica; Laatsch, Bethany; Lowater, Harrison; Hati, Sanchita (2021-04)Poly(ethylene glycol) (PEG) is a biocompatible, hydrophilic, flexible, non-toxic polyether commonly used in proteomics because it is widely regarded to be a biologically inert molecule. This includes PEG2000 (molecular ... -
Molecular Dynamics Simulation Studies to Probe the Impact of Oxidative Stress on the Binding of SARS-CoV-2 Spike Protein to Angiotensin-Converting Enzyme 2
Fossum, Carl; Lowater, Harrison; Narkiewicz-Jodko, Alexander; Laatsch, Bethany; Lonzarich, Leo; Hati, Sanchita; Bhattacharyya, Sudeep (2021-04)The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein as well as the human cell surface receptor angiotensin-converting enzyme II (ACE2) contain several cysteine residues. These cysteine residues exist either in ... -
Role of a Conserved Disulfide on the Interactions Between Severe Acute Respiratory Syndrome Coronavirus 2 and Angiotensin-Converting Enzyme 2
Walk, Gavin; Titera, Noah; Sparks, Hailee; Schierenbeck, Jacqueline; Rocksvold, Alexander; Running-Fischer, Charles; Laatsch, Bethany; Lowater, Harrison; Bhattacharyya, Sudeep (2021-04)Coronaviruses are large, enveloped, positive strand RNA viruses capable of infecting a large array of mammalian and avian species that possess densely glycosylated spike-shaped proteins on their surfaces giving them the ...