Sex Difference in 17-beta Estradiol Regulation of Akt Signaling with Estrogen Receptor Alpha Activation
Abstract
There is evidence of a sex difference in the incidence and outcome of Alzheimer's disease and stroke. Females have a better outcome than males. However when women reach menopause, this neuroprotection in females is lost. The loss of neuroprotection in menopause suggests that E2 (estradiol) regulates this sex difference in neuroprotection. The purpose of this study was to test the hypothesis that there is a sex difference in 17 beta-estradiol regulation of Akt signaling with Estrogen Receptor Alpha activation in prenatal neurons.
Subject
Neuroprotection--Sex difference
17 beta-estradiol
Akt/PKB signaling pathway
Posters
Estrogen receptors
Permanent Link
http://digital.library.wisc.edu/1793/70001Type
Presentation
Description
Color poster with text, charts, and graphs.