Effects of Bupropion and Naltrexone on the Discriminative Stimulus Effects Produced by 22 Hours Food Deprivation

File(s)
Date
2014-04Author
Toddes, Carlee
Barlow, Molly A.
Olson, K.J.
Berti, Brianna
Vanden Avond, Mark A.
Advisor(s)
Jewett, David C.
Metadata
Show full item recordAbstract
Bupropion inhibits dopamine and norepinephrine transporters and is clinically used to treat
depression and as a smoking cessation aid. Naltrexone is an opioid antagonist and is clinically used to treat opioid and alcohol dependence. Studies show that bupropion decreases food intake in rats (Zarrindast, Hosseini-Nia, 1988). Naltrexone has also been shown to decrease food intake in rats (Kirkham, Blundell, 1987). Bupropion in combination with naltrexone decreases
food intake in rats (Clapper, Athanacio, Wittmer, Griffin, D'Souza, Parkes, & Roth, 2013). The purpose of this study was to examine the effects of bupropion, naltrexone, and combinations of bupropion and naltrexone in non-restricted rats
trained to discriminate between 22- and 2-hr food deprivation to gain better understanding of
neurochemicals mediating the discriminative stimulus e ects of 22-hr food deprivation.
Subject
Naltrexone--Side effects
Hunger--Psychological effects
Discrimination learning
Posters
Rats--Training
Buproprian--Side effects
Permanent Link
http://digital.library.wisc.edu/1793/69796Description
Color poster with text and graphs.
Part of
Related items
Showing items related by title, author, creator and subject.
-
The Effects of Physical Activity on Adverse Side Effects in Chemotherapy Patients
Long-Pero, Maddisen (Office of Student Research and Creative Activity, 2018-12)Each year, more than 14 million people worldwide are diagnosed with cancer. Despite advancements in medicine, a cure for this disease has not been found. Chemotherapy, a common cancer treatment, is often used in an attempt ... -
The effects intimate partner violence has on children: Addressing the effectiveness of interventions and therapy
Carroll, Jessica (2018-02-27)