A special case of judging compliance is when the effluent limit is set at a level below the method limit of detection (MDL) of the substance being monitored. In many such cases, almost all measurements on the effluent are ...

Steepest ascent is an important tool for process improvement. This report discusses how to use the steepest ascent method in the context of constrained designs. The properties of the projection designs proposed in Report ...

Experimental design is a powerful tool for quality improvement. In some situations, however, the design variables are subject to multiple linear constraints. In this report, we propose a class called projection designs ...

This paper discusses the experience of a knowledge-based organization in the pharmaceutical industry in building a fundamental capability for implementing strategic transformation. The organization developed and implemented ...

In this report, we discuss the analysis of projection designs proposed in Report #53. We show that analyzing projection designs is essentially the same as analyzing some traditional unconstrained designs such as factorial ...

In response to disturbing challenges ahead, leaders at the University of Wisconsin-Madison are committed to transform the institution to a Total Quality University. As a pilot project in the transformation, this paper ...