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Now showing items 11-20 of 47
Synthesis and Antibody Binding Study of MUC1 Mucin Peptides with Unnatural Backbones
(2018-02-08)
The MUC-1 mucin is a heavily glycosylated transmembrane
protein found on the apical surface of epithelial cells with a
short cytoplasmic end and a longer extracellular domain
consisting of multiple 20-amino acid tandem ...
Smart Diblock Copolymers for Enhanced Oil Recovery Applications
(2015-04)
The purpose of this study was to examine the benefits and drawbacks of enhanced oil recovery (EOR).
Computational Docking of Mucin Peptide Derivatives with SM3 Antibody
(2018-05)
The crystal structure of the mucin monoclonal antibody SM3 complexed with a 13 amino acid MUC1 mucin peptide was determined. The high selectivity of the SM3 antibody to the aberrant carbohydrate cancer mucin peptide suggests ...
Investigating Catalytically Important Residues in Escherichia coli Prolyl-tRNA Synthetase Through Site-Directed Mutagenesis
(2017-11-30)
In the present study, we have employed
site-directed mutagenesis to probe the role of four residues in E. coli ProRS (Ec
ProRS) on the overall catalytic function. Specifically, we examined the impact of
changes in amino ...
Synthesis, Characterization and Applicability of Reactive Biomimetic Complexes Towards Important Biological Reactions
(2015-04)
This study involves the development, synthesis, and characterization of new biomimetic model systems consisting of a tetra-dentate N3[subscript]O-containing ligand (BPG) and divalent first-row transition metal ions observed ...
Quantum-Chemical Study of Hydrogen-Bonded Complexes : Understanding Solvent Shifts in the IR Spectra of Alcohols
(2015-04)
Initially, we were interested in whether the
hydrogen bonding in HF (l) or in H2O (l) is
stronger. Therefore, we examined a series of binary
complexes involving HF & H2O: (H2O)2, (HF)2, and three isomers of H2O/HF. We ...
Development of a Fluorescence Excitation Spectroscopy System
(2015-04)
The overall goal of our experimental research program is to determine bond properties, such as vibrational frequencies, for small molecules.
Studying the Effects of Varying pH and Temperature on the Smart Polymer mPEG-block-PDMAEMA
(2018-04)
“Smart polymers” change their mechanical properties in response to changes in stimuli, such as pH, temperature, and polymer concentration. We chose to focus on the viscoelastic properties when determining the effects of ...
Structural and Energetic Properties of FCH2CN-GeF4 and CICH2CN-GeF4 Via Low-Temperature IR Spectroscopy and Computations
(2015-04)
The present study deals with nitrile-GeF4 complexes. We hypothesize that adding electronegative halogens to the nitrile will weaken the complex and enhance them.
Cavity Ringdown Spectrum of 2-Cyclohexen-1-one in Its Lowest Singlet Excited State
(2014-04)
The overall goal of our experimental research program is to determine bond properties, such as vibrational frequencies, for small molecules. Such data may be used by computational chemists to verify their theoretical ...










