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    Calculation of Binding Free Energies of NAD(P)H:Quinone Oxidoreductase 1 Inhibitors 

    Bhattacharyay, Sudeep; Zajac, Jonathan W.P. (2018-04)
    NAD(P)H:quinone oxidoreductase 1 (NQO1) plays a key role in cellular defense in humans. It is known to reduce quinones to hydroquinones, inhibiting their ability to become a free radical semiquinone state, and cause cellular ...
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    Investigating Structure-Dynamics-Function Differences Among Various Species of Proyl-tRNA Synthetase Using a Hybrid QM/MM Computational Technique 

    Weinzetl, Murphi; Fossum, Carl; Narkiewicz-Jodko, Alexander; Hati, Sanchita; Bhattacharyay, Sudeep (2019-05)
    All living organisms contain amino-acyl tRNA synthetases (AARSs) ‒ a family of enzymes critical for protein synthesis. They are responsible for the covalent ligation of proline to its specific tRNA molecule, called tRNAPro, ...
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    Use of Geometrical Docking Algorithm to Explore Species Specific Differences in Proyl-tRNA Synthetases 

    Bhattacharyay, Sudeep; Theisen, Cole; Reinhardt, Clorice R. (2018-02-08)
    Prolyl-tRNA synthetases belong to a class of enzymes that play a pivotal role in the protein synthesis. These enzymes are responsible for attaching the amino acid, proline, to the 3’ end of the prolyl-tRNA. The structures ...
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    Flipping the General Chemistry Laboratory Lecture : Increasing Student Engagement by Enhancing Self-Directed Learning 

    Idárraga, Katrina; Nenning, Hannah T.; Theisen, Roslyn M. (2019-05)
    Strengthening instruction in STEM fields can benefit student learning as well as foster positive attitudes towards the sciences. This project tries to answer the question whether there is a measurable difference in ...
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    How Much is Too Much : Testing the Boundaries of Hydrogen Bonded Liquid Crystal/Inhibitor Networks 

    Lindberg, David; Wiegel, Kurt N. (2019-05)
    A liquid crystal is state of matter that simultaneously displays properties of both a liquid and a solid. Liquid Crystals have applications in liquid crystal displays (LCD’s) and optical imaging. Liquid crystals or “mesogens” ...
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    Development of Butlerov's Structural Theory, 1859-1862 

    Raspel, Sergei N.; Rothbauer, Dylan R.; Goedhart, Carly S.; Lewis, David E. (2018-04)
    In 1859, Aleksandr Mikhailovich Butlerov (1828-1886) had just returned to Kazan after spending akomandirivka (official study leave) in the laboratory of Charles Adolphe Wurtz (1817-1884) in Paris, where he became a member ...
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    Analysis of the Antibody Binding of Derivative MUC1 Peptides via STD NMR 

    Lynch, Andrew R. (2015-04)
    This study analyzes the binding ability of the peptide GVTSAPD, an upstream sequence preceding PDTRP, as well as six derivative peptides against specific mouse MUC1 mucin monoclonal antibody (IgG1, 6A4) by Saturation ...
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    Purification of Copper-Free Methanobactin-SB2 to Analyze its Shape-Shifting Behavior 

    Matheka, Faith; Toycen, Kaitlin (2015-04)
    We are interested in isolating the copper-free forms of methanobactin, which presents a challenge, since they are much more unstable and difficult to characterize than the copper bound forms that we and others have worked ...
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    Synthesis of Cyclic Antigenic MUC1 Mimotopes 

    Lynch, Andrew R.; Yang, Thao (2017-12-01)
    The immune system responds to antigens via specific sequences called epitopes. The antibody binding amino acid epitope PDTRP within the variable tandem repeat (VNTR) domain of the Mucin1 (MUC1) transmembrane epithelial ...
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    Metal Sequestration During Aggregation Based Crystal Growth 

    Hooper, Robert L.; Plaziak, Charles (2018-01-09)
    This project is focused on determining how associated metals of environmental concern (especially Pb) behave during aggregationbased crystal growth as a function of increasing Crystallinity Index (CI).
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    AuthorYang, Thao (5)Glogowski, Elizabeth M. (4)Bhattacharyay, Sudeep (3)Laskowski, Elizabeth (3)Lewis, David E. (3)Lynch, Andrew R. (3)Stubbs, Elizabeth (3)Hati, Sanchita (2)Her, Lysengkeng (2)Lindberg, Charles (2)... View MoreSubject
    Chemistry (47)
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    Smart polymers (6)Department of Chemistry (3)Mucin peptides (3)PDTRP (3)PEG-PDMAEMA (3)Prolyl-tRNA synthetase (3)Antibody binding (2)Chemistry education (2)... View MoreDate Issued2015 (19)2018 (12)2017 (10)2019 (5)2014 (1)Has File(s)
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