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Synthesis of Cyclic Antigenic MUC1 Mimotopes
(2017-12-01)
The immune system responds to antigens via specific sequences called
epitopes. The antibody binding amino acid epitope PDTRP within the variable
tandem repeat (VNTR) domain of the Mucin1 (MUC1) transmembrane
epithelial ...
Investigating Catalytically Important Residues in Escherichia coli Prolyl-tRNA Synthetase Through Site-Directed Mutagenesis
(2017-11-30)
In the present study, we have employed
site-directed mutagenesis to probe the role of four residues in E. coli ProRS (Ec
ProRS) on the overall catalytic function. Specifically, we examined the impact of
changes in amino ...
Structural and Energetic Properties of H[3]N-GeF[3]CH[3] and Analogous Lewis Acid-Base Complexes (N-MX[3]-R)
(2017-04-19)
We
are
investigatingg
molecular
complexes
that
are
prone
to
condensed-phase
structural
changes.
A
molecular
complex,
in
general
terms,
is
any
association
of
two
otherwise
stable
molecules.
Tuning Smart Properties of mPEG-block-PDMAEMA Through Polymer Composition
(2017-11-15)
The purpose of this study was to study smart polymers. “Smart” polymers respond to changes in their environment with
a measureable change in property. Some smart polymers can
change their solubility when the conditions ...
Steric and Catalytic Effects of Alcohols on the Transamination of Napthalimides
(2017-11-14)
This experiment describes a systematic study of the effects of the size of
alcohols on the transamination of N-(3-chlorophenyl)-4-chloro-1,8-
naphthalimide.
When Push Comes to Shove : Limitations of Hydrogen Bonded Liquid Crystal/Inhibitor Networks
(2017-11-22)
A liquid crystal is state of matter that simultaneously displays properties of
both a liquid and a solid. Liquid crystals have applications in liquid crystal
displays (LCDs) and optical imaging technology. Liquid crystals ...
An IR and Computational Study of Pyridine-HCI and Its Fluorinated Analogs
(2017-03-28)
Condensed phase effects on structure/bonding H-bonded complexes, e.g. H[3]N-HCI, CH[3]CN-HCI. A key issue is how medium effects affect extent of proton transfer. We are exploring pyridine and its fluorinated analogs as N ...
Optimizing the Sensitivity of Particulate Silica Quantification by Molybdenum Blue Absorbance Spectrometry
(2017-04-17)
The purpose of this study was to develop a novel analytical method for quantifying respirable, airborne silicon containing particles.
Synthesis and Characterization of a Reversible and Tunable Smart Polymer
(2017-04-03)
Polymers are made of covalently bonded repeat units, called monomers, which make up long chains. The structure can be controlled to achieve a diblock copolymer with two different repeat units connected in blocks. “Smart” ...
An Explanation of a-Cyanocinnamate Esters as a Replacement for DEAD in the Mitsunobu Reaction
(2017-12-22)
The Mistunobu reaction was first reported by Oyo Mitsunobu in the Bulletin of the Chemical Society of Japanin 1967, with a follow-up review in Synthesisin 1981. A recent literature search using Web of Science reveals that ...