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Worms, Genetics and Healthy Kidneys : the Candidate PKD-2 Localization Factor, papl, May Play a Role in Polycystic Kidney Disease
Polycystic Kidney Disease (PKD) causes cysts to form within the kidneys, leading ultimately to renal failure. Prior research in our lab demonstrated that expression of the papl gene is downregulated in a zebrafish model ...
Zebrafish, Genes, and Human Kidneys : Gene Mapping in Zebrafish Mutants May Help Uncover Genetic Roots of Polycystic Kidney Disease
Patients with autosomal dominant polycystic kidney disease (ADPKD) suffer from disrupted kidney function due to large, fluid-filled cysts that form in the collecting ducts and kidney tubules. Current treatments for the ...