The crystal structure of the mucin monoclonal antibody SM3 complexed with a 13 amino acid MUC1 mucin peptide was determined. The high selectivity of the SM3 antibody to the aberrant carbohydrate cancer mucin peptide suggests ...

The MUC-1 mucin is a heavily glycosylated transmembrane protein found on the apical surface of the epithelial cells that contains a short cytoplasmic end and a long extracellular domain consisting of multiple 20-amino acid ...