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Exploring Senataxin -- Sen1p homology
Mutated SETX, a human gene encoding for the protein Senataxin, has been identified among patients with two different neurodegenerative disorders--ataxia-ocular apraxia 2 (AOA2) and amyotrophic lateral sclerosis 4 (ALS4). ...
Feasibility study: Comparison of performance status with objective physical activity monitors in lung cancer patients
Context: Performance status (PS) is a predictor of response to chemotherapy but difficult to identify in patients with advanced lung cancer. It is measured using the ECOG scale, which relies on simple questions to assign ...
TRPV1 mediates matrix metalloproteinase expression in spinal cord injury-induced chronic neuropathic pain
Neuropathic pain (NP) is common following spinal cord injury (SCI). Evidence exists for the involvement of many processes in NP development following SCI (Cain et al, 2007). Our past studies identified increased expression ...
Gaze-evoked blinks in rhesus monkeys
Gaze-evoked blinks, blinks that occur during rapid movements of the head and eyes, are believed to be the result of a shared mechanism that is responsible for a blink occurring with a saccade. In humans, it has been found ...