Now showing items 1-5 of 5
The Biochemical Characterization of a Translational Repressor
Iron regulatory proteins (IRP) are crucial post-transcriptional regulators of iron metabolism. They influence the synthesis of proteins involved in iron uptake, storage and use by binding to their mRNAs. IRP1 stands out ...
Comparison of non-heme liver iron and iron metabolism protein levels in superoxide dismutase 1 knock-out mice versus superoxide dismutase 1 wild-type mice
Iron is an important micronutrient that is necessary for multiple cellular functions. However, iron levels must be tightly regulated in order to prevent iron-deficiency and iron-toxicity. There are many proteins involved ...
Mid-life dementia risk scores as a predictor of CSF biomarker and cognitive response to simvastatin therapy in asymptomatic adults at risk for Alzheimer's disease: The ESPRIT trial
BACKGROOUND: Cardiovascular risk factors at mid-life are associated with an increased risk of developing Alzheimer's disease (AD). OBJECTIVE: Determine relationships between baseline dementia risk, cognitive function, CSF ...
Importance of CCW12 gene expression in zinc deficient Saccharomyces cerevisiae
Pathogenic fungi have a major impact on human health. There is a lack of good therapies and some pathogenic fungi are resistant to the existing treatments. One possible target for treatment is covalently bonded cell wall ...
Photo Voice: Application of a Novel Assessment Tool to Identify the Need to Improve Water Safety in Mountain Communities in the Dominican Republic
The mountain communities in the Elias Pina province of the Dominican Republic have the highest prevalence rates of diarrheal disease in the country. Using the participatory method of Photo Voice, the researcher partnered ...