Now showing items 1-10 of 10
α7-Nicotinic Acetylcholine Receptor Signaling in Cardiac Regeneration
Heart disease is the leading cause of death in the U.S. Loss of heart regenerative capacity in adult mammals is a principle reason why adults fail to recover from heart diseases. In contrast, neonatal mammals possess ...
Improving the Production of Terpenes by Recombination of 1-Deoxy-D-Xylulose 5-Ph
The Prevalence of Clostridium difficile in the Wisconsin Area and the Role of Dietary Fiber on Colonization
Clostridium difficile is an opportunistic pathogen. Since antibiotics alter a human’s microbiota, hospitalized patients are more likely to become infected with C. difficile. Studies have shown that a high-fiber diet can ...
Characterization of Listeria monocytogenes isolates from lactating dairy cows in a Wisconsin farm: antibiotic resistance, mammalian cell infection, and impacts on the fecal microbiota
(Journal of Dairy Science, 2021)
Listeria monocytogenes is an invasive foodborne pathogen that is ubiquitously present in the dairy farm environment. Although cattle are a reservoir of L. monocytogenes, most adult animals do not exhibit clinical symptoms, ...
Examining the Role of GRHL2 in Collagen and Spheroid Structures
Defining the molecular determinants required for RNA binding functions of the Bicaudal-C (Bicc1) translational repressor protein
Bicaudal-C (Bicc1) is an RNA binding protein that functions as translational repressor in all animal species. Its repression activities are required for a multitude of biological processes such as guiding the earliest steps ...
Novel insight into the patterns of in vitro short abortive RNA release by Escherichia coli RNA polymerase
E. coli RNA polymerase (RNAP) catalyzes prokaryotic transcription with the σ70 specificity factor, which directs the binding of RNAP to promoter DNA. RNAP operates on the promoter to form an open complex. In transcription ...
Investigation of the Genome-Wide Distribution of Histone Variant H3.3
Epigenetic regulation via loci-specific deposition of variant histone proteins is important for genome stability and regulation of gene expression. Replication-independent histone variant H3.3 has been implicated in ...
GBT440 increases hematocrit and improves biventricular function in Berkeley sickle cell disease mice
Sickle cell disease (SCD) is a hereditary blood disorder affecting millions of people in which red blood cells become sickled and lyse easily driven by polymerization of hemoglobin. Chronically, SCD causes anemia and ...
Do Amazon Fulfillment Centers Help or Harm Local Economies?
In this paper, I investigate the Amazon Corporation’s impact on the economic well-being of the communities that house its warehouses, or “Fulfillment Centers.” A review of the literature surrounding Amazon’s economic impact ...