College of Agricultural and Life Sciences, UW-Madison
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INVESTIGATING THE ROLE OF THE MEMBRANE LOCALIZATION DOMAIN (MLD) IN BOTULINUM NEUROTOXIN A (BoNT/A) DURATION OF ACTION
(University of Wisconsin-Madison, 2025-08-26)Botulinum neurotoxins (BoNTs), produced by Clostridium botulinum, are among the most potent biological toxins known to humans and are the causative agents of botulism, a severe neuroparalytic disease 1. Among the BoNT ... -
Center and Institute Directory
(MINDS@UW, 2024)This data set catalogues locations and work of sustainable agriculture and food-focused centers and institutes based at U.S. land grant and R1 universities. It does not include schools, programs, clinics, etc.. The database ... -
The Contribution of Agriculture to the Wisconsin Economy: An Update for 2022
(2024-11-18)This study provides an update on the Contribution of Agriculture to the Wisconsin Economy undertaken by Deller (2019) using data for 2022, the most current available. Despite the declining number of farms between 2017 ... -
Bridging a major disconnect: ideas for farm standards and systems to achieve phosphorus goals in Wisconsin lakes and streams
(University of Wisconsin - Madison, 2024-09)Despite decades of effort to reduce agricultural nonpoint source pollution in Wisconsin, a gap remains between current on-farm practices and what would be needed to achieve water quality goals in lakes and streams. This ... -
Visual narrative vs. traditional slideshow for engaging youth in biodiversity education
(2024)Engaging youth in early and sustained conservation education has important implications for promoting positive attitudes and behaviors in those who will become the future of conservation and management. Towards this goal, ... -
Investigation of the role of CarD in transcription initiation and the stringent response in Zymomonas mobilis
(2023)In some prokaryotes, transcriptional regulator CarD stabilizes the open promoter complex during transcription initiation. As both a transcriptional activator and repressor, CarD can be used to coordinate gene expression ... -
The Effect of Alfalfa Perimeter Plantings on Strawberry Pollen Consumption by Syrphidae (Diptera) in Wisconsin
(2023)Syrphid flies visit flowers to feed on nectar and pollen and provide an important pollination service in many cropping systems. We previously observed that perimeter plantings of alfalfa concentrate syrphid populations ... -
Examining the multi-species impact on the built-space microbiome of a small-scale USDA inspected animal processing facility
(2023)The global population continues to expand, driving a need for increased food production, including animal-derived proteins from poultry, pork, beef, and lamb. In the US, large-scale processing facilities dominate the meat ... -
Investigation of the Contribution of the Stimulator of Interferon Genes (STING) Pathway to the Type I interferon response in Murine glioblastoma cell lines
(2023)Glioblastoma Multiforme (GBM) is a potent type of cancer due to its high mortality and aggressive nature with a median survival of 14 months post-diagnosis (1, 2). Immunotherapies are a promising approach to treating GBMs ... -
Determining the Role of Energy on Mammary Gland Utilization of Plasma Amino Acid
(2023)Our overall objective is to investigate nutritional strategies that upregulate signaling pathways of milk protein synthesis directing nitrogen towards milk production, therefore reducing the amount of nitrogen waste entering ... -
Analysis of StAR RNA Splicing and Lipid Droplets Composition in MA10 Cells Under Different Stimuli
(2023)Steroidogenic acute regulatory protein (StAR) is a transport protein which plays a key role in steroidogenesis. Different pathways can activate StAR transcription. cAMP activates PKA which phosphorylates CREB. PKA also ... -
Investigating the Binding Specificity of Polymorphic KIR Alleles with Potential Ligands
(2023)Natural killer (NK) cells are an important part of the immune response and play a vital role in the defense against viral pathogens. NK cell function is characterized by its ability to regulate cytotoxicity and modulate ... -
Determining the requirement for viral DNA amplification in mediating the reorganization of cellular chromatin during the Epstein-Barr virus lytic cycle
(2023)We have uncovered how Epstein-Barr virus (EBV) induces the reorganization of cellular chromatin (ROCC), where host chromatin is compacted and marginated within the nucleus. We tested the role of EBV lytic DNA amplification ... -
Do IRX3 and IRX5 Direct Cytoplasm Traffic Between Oocytes During Germline Cyst Breakdown?
(2023)Poor oocyte quality and a diminished ovarian reserve contribute significantly to female infertility. The ovarian reserve is determined by the finite supply of primordial follicles a woman has at birth. Evidence suggests ... -
Investigating the Role of SDHB in Cardiac Regeneration
(2023)Heart failure is the leading cause of death in the United States. The long wait for heart transplants and the risk of graft rejection has motivated heart regeneration research to advance heart failure treatment. Importantly, ...
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