Browsing by Subject "Naltrexone"

Now showing items 1-4 of 4

    • Discriminative Stimulus Effects of Naltrexone and Haloperidol in Rats With Chronic, Intermittent Access to Sucrose 

      Jewett, David C.; Marek, Morgan A.; Moline, Adam D.; Hadorn-Papke, Damin J.; Vogelsang, Jenna D.; Wallner, Michelle A.; Cyra, Matthew D.; Todd, Justin A.; Moe, Simon M.; Eichstadt, Rachel M.; Altendorf, Luke R.; James, Kimberly F. (2017-12-05)
      Our previous research has shown that naltrexone can be established as a discriminative stimulus for rats given daily sucrose solutions and trained under a 3.2 mg/kg training dose (TD). Our current study attempts ...

    • Discriminative stimulus effects of naltrexone in rats with limited access to sucrose 

      Marek, Morgan A.; Moe, Simon M.; De Roach, Elliott; Warner, Jamie; James, Kimberly F.; Altendorf, Luke R.; Paukner, Dawn; Thai, Calvin; Herrmann, Jody; Jewett, David C.; Rolefson, Kelsey; Moline, Adam D.; Eichstadt, Rachel M.; Wachholz, Blake; Edwards, Paige A.; Virnig, Austin (2017-03-14)
      Naltrexone, an opioid antagonist, is not discriminable at typical doses in operant paradigms. We attempted to establish naltrexone as a discriminative stimulus in rats given 12-hour dark cycle access to sucrose solutions. ...

    • Effects of Naltrexone in an Animal Model of Hunger. 

      Zellhoefer, Ashley S.; Nelson, Shannon K.; Sime, Lindsey N.; Peper, Angela D.; Bunker, Mitch R.; Dunbar, Andrew R.; Callahan, Jamie Marie; Weisenbeck, Emily R.; Benzel, Kristine N. (2009-04)
      Obesity is a leading cause of premature illness and death in the United States. We have developed a food deprivation discrimination task to investigate neurochemical and dietary factors that influence the discriminative ...

    • Effects of the Kappa Agonist U69,593 on Naltrexone’s Discriminative Stimulus Effect in Subjects Given Chronic, Intermittent Sucrose Access 

      Marek, Morgan A.; Schulz, Emily; Fruit, Nicholas A.; Vile, Oriana; Stutt, Hannah; Zajac, Jonathan W.P.; Dorn, Holly; Herzberg, Caitlin; Petrey, Alex; Rothbauer, Dylan; Brandt, Lucas J.; Jewett, David C. (2019-05)
      Naltrexone (NTX) is a non-specific opioid antagonist that is comparable to naloxone (Narcan). Avena, Hoebel & colleagues (2004) demonstrated that rats given access to a chronic, intermittent sucrose solution have increased ...